Citology, Ltd. secures Patent for cIToStack™
Citology, Ltd. Secures Patent for Revolutionary cIToStack™ Technology, Transforming Digital Pathology Data Management
PRAGUE, Czech Republic – cITology Ltd., a technology company specializing in solutions for digital cytopathology and precision medicine, today announced that it has been granted a patent for its proprietary cIToStack™ technology. This breakthrough invention addresses one of the most critical bottlenecks in digital cytopathology: the management of massive Whole Slide Imaging (WSI) data.
As digital cytopathology adoption accelerates, laboratories and hospitals face escalating costs related to data storage and hardware requirements. WSI files, particularly those used in cytology, are notoriously large and difficult to manage. Citology’s newly patented cIToStack™ offers a scanner-independent solution that dramatically reduces file sizes while maintaining absolute data integrity.
Breaking Down the Data Barrier
The cIToStack™ technology is compatible with various scanner image formats, making it a versatile tool for diverse clinical environments. Its primary innovation lies in its ability to compress WSI files significantly without the loss of primary cell data—a crucial requirement for accurate medical diagnosis.
Performance benchmarks for the technology have shown impressive results. For a typical Cerebrospinal Fluid (CSF) cytology sample, cIToStack™ successfully reduced file sizes from the standard 4–5.5 GB down to just 0.4–1.2 GB.
Furthermore, this efficiency does not come at the cost of workflow speed.
A Triumph of Collaboration and Strategy
The granting of this patent marks a major milestone for the Prague-based company, validating years of research and development.
“This achievement is the result of two years of intensive work and close collaboration with partners from both academia and clinical practice,” said Milan Prochazka, Founder of Citology, Ltd. “Our goal was to solve a fundamental infrastructure problem without compromising diagnostic quality. This patent validates that effort and underlines our aim to build an efficient and robust IP strategy around our inventions as we continue to scale.”
Enhancing Clinical Precision
Beyond the IT and cost-saving benefits, the technology is designed to improve the daily workflow of pathologists.
Ondrej Sobek, Founder & Medical Lead at Citology, Ltd., highlighted the medical impact of the invention: “cIToStack™ represents a genuine clinical leap. By streamlining data management, we hope this invention helps cytopathologists read WSI slides more precisely and efficiently. Removing the burden of heavy data handling allows the focus to remain squarely on the cellular details essential for precision medicine.”
About Citology, Ltd.
Based in Prague, Citology, Ltd. is a pioneer in the field of digital cytopathology and precision medicine. The company develops cutting-edge software solutions designed to optimize diagnostic workflows, manage medical imaging data, and support the future of AI-driven diagnostics.

